Disappearance kinetics of solutes from synovial fluid after intra- articular injection.
نویسندگان
چکیده
منابع مشابه
Synovial perfusion and synovial fluid solutes.
answer goes back to the cardinal signs of inflammation. The redness and heat of this state relate directly to increased local blood supply, and these critical findings cannot be examined systematically without accurate quantification of flow. Further, the imbalances of vascular permeability and tissue clearance that lead to tissue swelling cannot be evaluated usefully without an understanding o...
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OBJECTIVE The aim of this prospective study was to find if a complete synovial fluid aspiration before injecting intra-articular corticosteroids influences the treatment result. METHODS The study was performed in 147 patients with rheumatoid arthritis (RA). One hundred and ninety one knees with synovitis were randomised to arthrocentesis (n=95) or no arthrocentesis (n = 96) before 20 mg triam...
متن کاملSerial studies of synovial fluid in evaluating intra-articular agents.
One of the most difficult problems in the study of rheumatic diseases is the evaluation of an antiinflammatory response. That this is true in intraarticular as well as systemic therapy is illustrated by the divergence of results reported in the literature. For example, Cohen and others (1954) concluded, by purely clinical evaluation in a large number of patients, that cortisone acetate was equa...
متن کاملChanges in concentrations of haemostatic and inflammatory biomarkers in synovial fluid after intra-articular injection of lipopolysaccharide in horses
BACKGROUND Septic arthritis is a common and potentially devastating disease characterized by severe intra-articular (IA) inflammation and fibrin deposition. Research into equine joint pathologies has focused on inflammation, but recent research in humans suggests that both haemostatic and inflammatory pathways are activated in the joint compartment in arthritic conditions. The aim of this study...
متن کاملSynovial fluid-derived mesenchymal stem cells increase after intra-articular ligament injury in humans.
OBJECTIVE The existence of mesenchymal stem cells (MSCs) in SF was previously reported. However, the behaviour and properties of MSCs derived from SF have not been fully elucidated. METHODS Human SFs were obtained from 19 knee joints with anterior cruciate ligament injury around the time of reconstruction surgery, and from three healthy volunteers. SF was plated, cultured and examined for col...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 1994
ISSN: 0306-5251
DOI: 10.1111/j.1365-2125.1994.tb04365.x